Momoko Sakura is an elementary school student who likes popular idol Momoe Yamaguchi and mangas. She is often called "Chibi Maruko-chan" due to her young age and small size. She lives together with her parents, her grandparents and her elder sister in a little town. In school, she has many friends with whom she studies and plays together everyday, including her close pal, Tama-chan; the student committee members, Maruo-kun and Migiwa-san; and the B-class trio: 'little master' Hanawa-kun, Hamaji-Bu Taro and Sekiguchi-kun.